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Protein quality control in neurodegenerative diseases

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  • 148 stron
  • 6 godzin czytania

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The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

Zakup książki

Protein quality control in neurodegenerative diseases, Richard I. Morimoto

Język
Rok wydania
2013
Oprawa
(twarda)
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Tytuł
Protein quality control in neurodegenerative diseases
Język
angielski
Wydawca
Springer
Rok wydania
2013
Oprawa
twarda
Liczba stron
148
ISBN10
3642279279
ISBN13
9783642279270
Seria
Opis
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.