Applied Biopharmaceutics and Pharmacokinetics

Więcej o książce

This comprehensive textbook on biopharmaceutics and pharmacokinetics has been a leading resource for over three decades. The sixth edition offers a foundational understanding of these principles and their application to drug product development, performance, and therapy. It uniquely addresses the complexities of ensuring safe and effective drug therapy. Authored by experts with both academic and clinical backgrounds, the text enables readers to grasp essential concepts in the field. Key learning outcomes include the ability to analyze raw data to derive pharmacokinetic models and parameters that accurately describe drug absorption, distribution, and elimination. Readers will also learn to critically evaluate biopharmaceutic studies related to drug product equivalency and design effective dosage regimens using pharmacokinetic and biopharmaceutic parameters. The book emphasizes detecting clinical pharmacokinetic issues and applying basic principles to resolve them. Each chapter features practical problems and clinical examples to facilitate the application of concepts to patient care and drug consultation. Additionally, Chapter Objectives, Summaries, and Frequently Asked Questions guide readers in focusing on key ideas. Most chapters have been updated to reflect the latest insights into drug performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.