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Calcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side effects associated with that mechanism of action. These drugs offer an exciting alternative approach to the treatment of heart failure, and this volume provides an authoritative overview of the physiology, biochemistry, and clinical issues involved. It will be of interest to pharmacologists, research and clinical cardiologists, and physiologists.
Zakup książki
Modulation of Cardiac Calcium Sensitivity, John A. Lee, David G. Allen
- Język
- Rok wydania
- 1993
- Oprawa
- (twarda)
Metody płatności
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- Tytuł
- Modulation of Cardiac Calcium Sensitivity
- Podtytuł
- A New Approach to Increasing the Strength of the Heart
- Język
- angielski
- Autorzy
- John A. Lee, David G. Allen
- Wydawca
- Oxford University Press
- Rok wydania
- 1993
- Oprawa
- twarda
- Liczba stron
- 368
- ISBN10
- 0192623478
- ISBN13
- 9780192623478
- Seria
- Kategorie
- Opis
- Calcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side effects associated with that mechanism of action. These drugs offer an exciting alternative approach to the treatment of heart failure, and this volume provides an authoritative overview of the physiology, biochemistry, and clinical issues involved. It will be of interest to pharmacologists, research and clinical cardiologists, and physiologists.