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Recent Results in Cancer Research - 54: Malignant Bone Tumors

VIth International Symposium of the Gesellschaft zur Bekämpfung der Krebskrankheiten Nordrhein-Westfalen e.V., Düsseldorf, October 17/18 1974

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Bone tumors hold a unique position among human tumors due to their rarity and the recent establishment of reliable diagnostic criteria, developed over the last thirty years. An international classification code was outlined five years ago and has been critically applied by various working groups, yielding mixed results. The complexity of histologic manifestations in neoplastic bone presents challenges; even top diagnostic histologists can classify only about 85% of bone tumors using the proposed system. The fascination with osteoclastic giant cells has led to the misdiagnosis of "brown giant cell tumor" for various osteoclastic tumors, regardless of their benign or malignant nature. The classification of "giant cell tumors" remains contentious, particularly concerning their malignancy and benignity, and definitive conclusions will require extensive follow-up studies. However, progress is being made with the establishment of regional bone tumor registries in various countries, inspired by the American model, including efforts in the German Federal Republic.

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Recent Results in Cancer Research - 54: Malignant Bone Tumors, Ekkehard Grundmann, Gesellschaft zur Bekämpfung der Krebskrankheiten Nordrhein-Westfalen

Język
Rok wydania
1976
Oprawa
(twarda)
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Tytuł
Recent Results in Cancer Research - 54: Malignant Bone Tumors
Podtytuł
VIth International Symposium of the Gesellschaft zur Bekämpfung der Krebskrankheiten Nordrhein-Westfalen e.V., Düsseldorf, October 17/18 1974
Język
angielski
Wydawca
Springer
Rok wydania
1976
Oprawa
twarda
Liczba stron
282
ISBN10
3540075194
ISBN13
9783540075196
Seria
Opis
Bone tumors hold a unique position among human tumors due to their rarity and the recent establishment of reliable diagnostic criteria, developed over the last thirty years. An international classification code was outlined five years ago and has been critically applied by various working groups, yielding mixed results. The complexity of histologic manifestations in neoplastic bone presents challenges; even top diagnostic histologists can classify only about 85% of bone tumors using the proposed system. The fascination with osteoclastic giant cells has led to the misdiagnosis of "brown giant cell tumor" for various osteoclastic tumors, regardless of their benign or malignant nature. The classification of "giant cell tumors" remains contentious, particularly concerning their malignancy and benignity, and definitive conclusions will require extensive follow-up studies. However, progress is being made with the establishment of regional bone tumor registries in various countries, inspired by the American model, including efforts in the German Federal Republic.