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Nongenotoxic Carcinogenesis

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The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic." On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.

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Nongenotoxic Carcinogenesis, A. Cockburn, Lewis L. Smith

Język
Rok wydania
1994
Oprawa
(twarda)
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Tytuł
Nongenotoxic Carcinogenesis
Język
angielski
Wydawca
Springer
Rok wydania
1994
Oprawa
twarda
Liczba stron
240
ISBN10
3540583424
ISBN13
9783540583424
Seria
Opis
The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic." On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.