Premeltons in DNA

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This book is written for a select group of research scientists working in the area of molecular and cellular biology. For this reason, the audience is likely to be professors of biology, chemistry, biochemistry and physics at a variety of universities, medical schools and their research institutes, along with their graduate students and postdoctoral fellows. Campus bookstores and science libraries could be the ideal place to market and to publicize a book such as this. The presence of premeltons in DNA leads to a unifying theory to understand much of DNA physical chemistry and molecular biology. Premeltons are predicted to define the 5' and 3' ends of genes in naked-DNA and DNA in active- chromatin, this having important implications for understanding physical-aspects of the initiation, elongation and termination of RNA-synthesis during transcription. For these and other reasons, the model will be of broader interest to the general-audience working in these areas. The model explains a wide variety of data, and carries with it a number of experimental predictions -- all readily testable -- as described within.