From Molecules to Networks

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An understanding of the nervous system at any analytical level necessitates knowledge of its fundamental unit, the neuron. This second edition provides a comprehensive foundation of the morphological, biochemical, and biophysical properties of nerve cells, thoroughly revised to reflect significant advances from the past five years. It expands on the network aspects of cellular neurobiology with a new chapter on Information Processing in Neural Networks, detailing the principles of operation and common circuit motifs in neural networks. Additionally, it explores the relationship between cellular processes and various neurological diseases. A new concluding chapter highlights how recent insights into the biochemical and biophysical properties of nerve cells have enhanced our understanding of neurodegenerative diseases. Written and edited by leading experts, this edition updates all chapters and discusses emerging knowledge about non-classical molecules influencing neuronal signaling. The book features full-color professional graphics throughout and introduces another new chapter on Molecular and Cellular Mechanisms of Neurodegenerative Disease, summarizing two decades of progress in understanding the cellular and molecular mechanisms behind disorders such as ALS, Parkinson's, and Alzheimer's disease.